| ORA | CASA | OSPITI | BET | RE | FIN | ESITO |
| 13:00 | Nuernberg | Greuther Fuerth | X | 1:1 | 0:1 | |
| 13:00 | FC Heidenheim | Jahn Regensburg | GOAL | 2:2 | 4:1 | HAI VINTO |
| 13:00 | Holstein Kiel | Wehen | 1 | 2:1 | 1:2 | |
| 13:00 | Osnabrueck | Bochum | X2 | 1:1 | 0:2 | HAI VINTO |
| 13:00 | Mariupol | Vorskla | 1X | 1:0 | 1:1 | HAI VINTO |
| 14:00 | Espanyol | Deportivo Alaves | X | 1:1 | 2:0 | |
| 15:30 | Wolfsburg | Freiburg | X2 | 1:1 | 2:2 | HAI VINTO |
| 15:30 | Fortuna Duesseldorf | Borussia Dortmund | 2 | 1:3 | 0:1 | HAI VINTO |
| 15:30 | Hertha Berlin | Eintracht Frankfurt | 1 | 2:1 | 1:4 | |
| 15:30 | FC Koln | Union Berlin | 1 | 2:0 | 1:2 | |
| 15:30 | Paderborn | Werder Bremen | 1X | 1:0 | 1:5 | |
| 16:00 | Zorya | Dynamo Kiev | 1X | 1:1 | 1:3 | |
| 17:00 | Hobro | Horsens | X2 | 1:1 | 1:1 | SUPERVINCITA |
| 17:00 | Celata Vigo | Villareal | 1X | 1:0 | 0:1 | |
| 17:00 | Racing Santander | Lugo | X | 0:0 | 1:2 | |
| 17:30 | Istanbul Basaksehir | Alanyaspor | 1 | 3:0 | 2:0 | HAI VINTO |
| 18:30 | Bayern Munich | Borussia M.Gladbach | 2 | 1:2 | 2:1 | |
| 18:30 | Olimpik Donetsk | Lviv | X2 | 0:1 | 2:0 | |
| 19:30 | Leganes | Real Valladolid | X | 1:1 | 1:2 | |
| 19:30 | Las Palmas | Girona | X2 | 0:0 | 0:0 | SUPERVINCITA |
| 20:00 | Besiktas | Antalyaspor | 1 | 2:1 | 1:2 | |
| 20:00 | Yeni Malatyaspor | Kasimpasa | X2 | 1:1 | 1:2 | HAI VINTO |
| 21:00 | Napoli | Inter | X2 | 1:2 | 1:1 | HAI VINTO |
| 21:30 | Saragozza | Alcorcon | 1 | 2:1 | 1:3 | |
| 22:00 | Braga | Boavista | 1 | 2:0 | 0:1 | |
| 22:00 | Maiorca | Barcellona | 2 | 1:2 | 0:4 | HAI VINTO |
